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Парацетамол оказался неэффективен против большинства видов боли – исследование

Парацетамол – օдин из самых популярных препаратов, которые люди принимают в борьбе с болью или повышенной температурой. Но, как оказалось, он далеко не так эффективен, как может показаться.

Ученые из University of Sydney проанализировали систематические обзоры 3570 исследований, в которых рассматривалась эффективность и безопасность парацетамола для снятия 44 видов болевых состояний. Как выяснилось, однократный или многократный прием стандартной дозы популярного препарата (0,5-1гр) превосходит плацебо только для 4 болезненных состояний – остеоартроза коленного и бедренного суставов, восстановления после трепанации черепа, болях в области таза, в том числе послеродовой, и головной боли напряжения.

Для таких распространенных состояний, как мигрень и головные боли на фоне простуды, а также боли в пояснице доказательства эффективности парацетамола были слишком низкого качества или неубедительны.

Стоит отметить, что ученые поставили под сомнение рекомендацию приема парацетамола при болях в пояснично-крестцовой области еще в 2016 году, когда рандомизированное плацебо-контролированное исследование с участием 1652 пациентов не выявило никакой разницы между популярным болеутоляющим и плацебо.